• Mechanochemical Cell Biology
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    Straube Lab
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    Spinning disk microscope...
    Mechanochemical Cell Biology

    iScat

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    First paper from Koester lab! In a collaboration with Marco and the Kukura lab, an in vitro membrane-tethered acto-myosin network was imaged with iSCAT microscopy. First author Lewis Mosby contributed the tracking software.
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    Phil reveals how the kinetochore protein CENP-F helps hold onto microtubules with one hand, while limiting the motorised stripping of corona components with the other
    >> Read the paper | [Link] |

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    Gabrielle has found a new type of vesicle in human cells. Intracellular nanovesicles or INVs are very small vesicles that transport proteins around the cell. INVs have been hidden from view until now.
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    Cansu developed dongle-knocksideways and her new paper describes how it works and some drawbacks of the technique.
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    We show how kinesin KIF1C is activated upon cargo binding.
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